Internal medicine

Enzyme

Oxidative stress

Carnitine

Disease

AMPK

Biology

Endocrinology

Polyunsaturated fatty acid

Chemistry

Docosahexaenoic acid

Insulin resistance

Hydroxytyrosol

Steatosis

Insulin

Steatohepatitis

Antioxidant

Fatty liver

Lipid metabolism

Metabolism

Polyphenol

Protein kinase A

Lipotoxicity

Fatty acid

Biochemistry

Medicine

Beta oxidation

Digestive and Liver Disease

Obesity-induced by high-fat diet (HFD) is associated with liver steatosis, oxidative stress and mitochondrial dysfunction, which can be eluded by the co-administration of the lipid metabolism modulator docosahexaenoic acid (DHA) and the antioxidant hydroxytyrosol (HT).

Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration