Understanding and managing metabolic dysfunction in Amyotrophic Lateral Sclerosis
Abstract
Introduction Amyotrophic Lateral Sclerosis (ALS) is a fatal motor neuron disease that leads to death after a median survival of 36 months. The development of an effective treatment has proven to be extremely difficult due to the inadequate understanding of the pathogenesis of ALS. Energy metabolism is thoroughly involved in the disease based on the discoveries of hypermetabolism, lipid/glucose metabolism, the tricarboxylic acid (TCA) cycle, and...
Paper Details
Title
Understanding and managing metabolic dysfunction in Amyotrophic Lateral Sclerosis
Published Date
Jul 13, 2020
Volume
20
Issue
9
Pages
907 - 919
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