Molecular mechanosensors in osteocytes
Abstract
Osteocytes, the most abundant and long-lived cells in bone, are the master regulators of bone remodeling. In addition to their functions in endocrine regulation and calcium and phosphate metabolism, osteocytes are the major responsive cells in force adaptation due to mechanical stimulation. Mechanically induced bone formation and adaptation, disuse-induced bone loss and skeletal fragility are mediated by osteocytes, which sense local mechanical...
Paper Details
Title
Molecular mechanosensors in osteocytes
Published Date
Jun 8, 2020
Journal
Volume
8
Issue
1
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