Assessing the effects of body weight on subchondral bone formation with quantitative 18F-sodium fluoride PET

The aim of this study was to quantify subchondral bone remodeling in the elbows, hands, knees, and feet using volumetric and metabolic parameters derived from 18F-sodium fluoride positron emission tomography (NaF-PET) and to assess the convergent validity of these parameters as an index of joint degeneration and preclinical osteoarthritis. A retrospective analysis was conducted in 34 subjects (32 males, 2 females) with metastatic bone disease...