Cucurbitacins: Bioactivities and synergistic effect with small-molecule drugs
Abstract
Cucurbitacins, widely found in plants belonging to the family of Cucurbitaceae, are highly oxidized tetracyclic triterpenes with various bioactivities, such as anticancer, anti-inflammatory, and liver protection. Among which, the anticancer activity of cucurbitacins is well studied. Cucurbitacins have been reported to promote apoptosis through the JAK/STAT3 pathway and the MAPK pathway. Cucurbitacins can block the cell cycle by inhibiting...
Paper Details
Title
Cucurbitacins: Bioactivities and synergistic effect with small-molecule drugs
Published Date
Sep 1, 2020
Journal
Volume
72
Pages
104042 - 104042
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