A novel mineralized high strength hydrogel for enhancing cell adhesion and promoting skull bone regeneration in situ

Bone defect therapy based on advanced biocomposite hydrogel scaffolds provide a promising strategy in bone tissue engineering. Inducing bone regeneration that meets the biomechanical, bioactivity and osteoconductivity criteria of bone tissue engineering is highly appealing but challenging. Here, we designed a mineralized, high-strength and tough nanocomposite hydrogel by in situ deposition of calcium phosphate hydroxide salt nanohydroxyapatite...