Original paper

Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective

Volume: 17, Issue: 6, Pages: 1330 - 1348
Published: May 25, 2020
Abstract
Stroke is a leading cause of death and disability. The pathophysiological mechanisms associated with stroke are very complex and not fully understood. Lysosomal function has a vital physiological function in the maintenance of cellular homeostasis. In neurons, CTSD (cathepsin D) is an essential protease involved in the regulation of proteolytic activity of the lysosomes. Loss of CTSD leads to lysosomal dysfunction and accumulation of different...
Paper Details
Title
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective
Published Date
May 25, 2020
Journal
Volume
17
Issue
6
Pages
1330 - 1348
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