Molecular mechanisms of interactions between BMP-2 and graphene: Effects of functional groups and microscopic morphology

Graphene and functionalized graphene are intensively studied as biomaterials for bone repair and regeneration. The interactions between graphene/functionalized graphene and key proteins implicated in bone repair are a key event for these applications, but the underlying mechanisms are insufficiently understood. Therefore, we performed molecular dynamics method to study the interactions between bone morphogenetic protein-2 (BMP-2) and perfect...