Sulfated modification, characterization, immunomodulatory activities and mechanism of the polysaccharides from Cyclocarya paliurus on dendritic cells

In this study, a crude and purified polysaccharide from Cyclocarya paliurus (CPP, CPP 0.05 ) were performed with chlorosulfonic acid–pyridine (CSA–Pyr) method to obtain sulfated derivatives (S-CPP, S-CPP 0.05 ). After comparatively investigating, characterization results showed that the modifications were successful. Polysaccharides were used to culture mouse bone marrow-derived dendritic cells (BM-DCs) to evaluate their immunomodulatory...