An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer
Abstract
The species specificity of papillomavirus has limited the development of an infection-based animal model to study HPV-associated head and neck carcinogenesis. Our study presents a novel in vivo model using the mouse papillomavirus MmuPV1 to study papillomavirus-associated head and neck cancer. In our model, MmuPV1 infects and causes lesions in both immunodeficient and genetically immunocompetent strains of mice. These virally induced lesions...
Paper Details
Title
An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer
Published Date
Jun 30, 2020
Journal
Volume
11
Issue
3
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