Tolerability and safety of dimethyl fumarate in relapsing multiple sclerosis: a prospective observational multicenter study in a real-life Spanish population

Dimethyl fumarate (DMF) tolerability and safety in multiple sclerosis (MS) has been analyzed in randomized clinical trials. Real-life studies are needed to assess possible harms of this therapy in a wider MS population. To evaluate DMF tolerability, safety and persistence in MS in a real-world setting. We conducted a multicenter prospective study of patients who started DMF, attended in 16 public hospitals of Spain. A specific database was...