2019-20 coronavirus outbreak

Pericardial effusion

Tamponade

Virology

Exertional dyspnea

Cardiology

Hydroxychloroquine

Myocarditis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Outbreak

Cardiac tamponade

Coronavirus disease 2019 (COVID-19)

Heart failure

Colchicine

Pericardiocentesis

Infectious disease (medical specialty)

Internal medicine

Cardiomyopathy

Medicine

Disease

JACC Case Reports

A 67-year-old woman presented with upper respiratory symptoms and was diagnosed with coronavirus disease-2019 (COVID-19). She was found to have a large hemorrhagic pericardial effusion with echocardiographic signs of tamponade and mild left ventricular impairment. Clinical course was complicated by development of takotsubo cardiomyopathy. She was treated with pericardiocentesis, colchicine, corticosteroids, and hydroxychloroquine, with improvement in symptoms. (Level of Difficulty: Intermediate.)

Cardiac Tamponade Secondary to COVID-19