Identification of a potential tumor suppressor gene, <i>UBL3</i>, in non-small cell lung cancer

Volume: 17, Issue: 1, Pages: 76 - 87
Published: Jan 1, 2020
Abstract

Objective:

Oncogenes have been shown to be drivers of non-small cell lung cancer (NSCLC), yet the tumor suppressing genes involved in lung carcinogenesis remain to be systematically investigated. This study aimed to identify tumor suppressing ubiquitin pathway genes (UPGs) that were critical to lung tumorigenesis.

Methods:

The 696 UPGs were silenced by an siRNA screening in NSCLC cells; the potential tumor suppressing UPGs were...
Paper Details
Title
Identification of a potential tumor suppressor gene, <i>UBL3</i>, in non-small cell lung cancer
Published Date
Jan 1, 2020
Volume
17
Issue
1
Pages
76 - 87
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