The Role of Immune Checkpoint Inhibitors in Colorectal Adenocarcinoma
Abstract
Over the past decade, immune checkpoint inhibitors (ICI) have proven to be promising agents in a number of solid tumor malignancies. Pembrolizumab and nivolumab are ICIs that target programmed cell death protein 1 and both have been approved by the US Food and Drug Administration for the treatment of microsatellite instability-high/DNA mismatch repair deficient (MSI-H/dMMR) colorectal cancer (CRC). In MSI-H/dMMR CRC, these agents were found to...
Paper Details
Title
The Role of Immune Checkpoint Inhibitors in Colorectal Adenocarcinoma
Published Date
Apr 3, 2020
Journal
Volume
34
Issue
3
Pages
349 - 362
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History