Clinical course of Japanese patients with early systemic sclerosis: A multicenter, prospective, observational study

To investigate the clinical course of Japanese patients with early diffuse cutaneous systemic sclerosis (dcSSc) and early SSc with interstitial lung disease (ILD). We prospectively analyzed the clinical features of 207 Japanese patients with early dcSSc (n = 150) and limited cutaneous SSc (lcSSc) with ILD (n = 57) in 10 medical centers every year for 7 consecutive years. Mean modified Rodnan total skin thickness score (mRSS) was 18.3 and 67.4%...