A multidimensional systems biology analysis of cellular senescence in aging and disease

Volume: 21, Issue: 1
Published: Apr 7, 2020
Abstract
Background Cellular senescence, a permanent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been linked to aging-related diseases. Many genes play a role in cellular senescence, yet a comprehensive understanding of its pathways is still lacking. Results We develop CellAge ( http://genomics.senescence.info/cells ), a manually curated database of 279 human genes driving cellular senescence, and perform...
Paper Details
Title
A multidimensional systems biology analysis of cellular senescence in aging and disease
Published Date
Apr 7, 2020
Volume
21
Issue
1
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