Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO ‐grade II —Report from the German/Swiss SIOP‐LGG 2004 cohort
Abstract
Reports on pediatric low‐grade diffuse glioma WHO‐grade II (DG2) suggest an impaired survival rate, but lack conclusive results for genetically defined DG2‐entities. We analyzed the natural history, treatment and prognosis of DG2 and investigated which genetically defined sub‐entities proved unfavorable for survival. Within the prospectively registered, population‐based German/Swiss SIOP‐LGG 2004 cohort 100 patients (age 0.8‐17.8 years, 4%...
Paper Details
Title
Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO ‐grade II —Report from the German/Swiss SIOP‐LGG 2004 cohort
Published Date
May 1, 2020
Volume
147
Issue
8
Pages
2159 - 2175
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