Coronavirus

2019-20 coronavirus outbreak

Adenocarcinoma

Betacoronavirus

Pleural effusion

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Outbreak

Coronavirus disease 2019 (COVID-19)

Radiology

Ground-glass opacity

Retrospective cohort study

Infectious disease (medical specialty)

Internal medicine

Medicine

Pneumonia

Gastroenterology

Pandemic

Atelectasis

Disease

Severity of illness

Cancer

Lung

Pathology

European Journal of Radiology

<h2>Abstract</h2><h3>Purpose</h3> To report CT features of coronavirus disease-2019 (COVID-19) in patients with various disease severity. <h3>Methods</h3> The CT manifestations and clinical data of 73 patients with COVID-19 were retrospectively collected in 6 hospitals from Jan 21 to Feb 3, 2020. We analyzed the initial and follow-up CT features of patients with disease severity, according to the Guidelines for the Diagnosis and Treatment of New Coronavirus Pneumonia. <h3>Results</h3> Six patients (8%) were diagnosed as mild type pneumonia; these patients had no obvious abnormal CT findings or manifested mild changes of lung infection. All 43 patients (59 %) with common type presented unique or multiple ground-glass opacities (GGO) in the periphery of the lungs, with or without interlobular septal thickening. In the 21 patients (29 %) with severe type, extensive GGO and pulmonary consolidation were found in 16 cases (16/21, 76 %) and 5 cases (24 %), respectively. An extensive "white lung", with atelectasis and pleural effusion were found in critical type patients (3, 4%). On the resolutive phase of the disease, CT abnormalities showed complete resolution, or demonstrated residual linear opacities. <h3>Conclusions</h3> Different CT features are seen according to disease severity, which can help COVID-19 stratification.

CT manifestations of coronavirus disease-2019: A retrospective analysis of 73 cases by disease severity