Engineering

Continuous glucose monitoring

Neuroscience

Pilocarpine

Continuous monitoring

Chromatography

Embedded system

Endocrinology

Economics

Hypoxia (environmental)

Computer science

SWEAT

Biochemical engineering

Organic chemistry

Continuous flow

Psychology

Oxygen

Epilepsy

Wearable computer

Internal medicine

Type 1 diabetes

Operations management

Medicine

Chemistry

Diabetes mellitus

Talanta

We present here wearable devices for continuous monitoring of diabetes and hypoxia based on continuous analysis of sweat. To induce sweating the clinically relevant procedure (pilocarpine electrophoresis) is used. Being a sufficient requirement for diagnostics, positive correlations in variation rates between glucose and lactate concentrations in sweat and the corresponding values in blood are shown. Continuous monitoring of human condition is possible only with the use of flow-through wearable devices providing a delivery of sweat to the biosensor almost immediately after secretion. Evaluating blood glucose through continuous sweat analysis upon glucose tolerance test, we clearly show that diabetics can actually be monitored reliably via non-invasive approach.

Wearable non-invasive monitors of diabetes and hypoxia through continuous analysis of sweat