Is the Use of Intraoperative Frozen Section During Pancreaticoduodenectomy Justified?

Intraoperative frozen section (IFS) is routinely utilized by many surgeons during pancreaticoduodenectomy. However, its utility has not been rigorously studied. Patients who underwent pancreaticoduodenectomy between 2006 and 2015 were identified from institutional data. Measures of diagnostic accuracy of frozen section and multivariate logistic regression are reported. The cohort included 1076 patients. Of resected specimens, 73.3% were...