Internal medicine

Radiology

Overdiagnosis

Prostate cancer

Prostate biopsy

Cancer

Magnetic resonance imaging

Biopsy

Prostate

Breast cancer

Core biopsy

Medicine

New England Journal of Medicine

The use of 12-core systematic prostate biopsy is associated with diagnostic inaccuracy that contributes to both overdiagnosis and underdiagnosis of prostate cancer. Biopsies performed with magnetic resonance imaging (MRI) targeting may reduce the misclassification of prostate cancer in men with MRI-visible lesions.

MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis