Applicability of biochar in water treatment is gaining interest due to its sustainability and low production cost. Herein, the biochar (BC) and activated biochar (ABC) synthesized from the cladodes of Opuntia ficus-indica (OFI) cactus were evaluated as a renewable adsorbent for adsorption of organic as well as inorganic pollutants including malachite green (MG) dye, Cu +2 and Ni +2 heavy metals. The modification of biochar with NaOH resulted higher surface basicity regarding more oxygen containing functional groups on the surface. The maximum uptake of 1341 mg g −1 , 49 mg g −1 and 44 mg g −1 onto activated biochar for malachite green dye, Cu +2 and Ni +2 was acquired through the best fitted Langmuir isotherm model. Pseudo-second-order and Elovich models were found to provide a suitable fit indicating towards the chemisorption of all three components. Film diffusion and chemisorption are the main steps in adsorption of MG dye and heavy metals on activated biochar. The adsorption mechanisms were also hypothesized for adsorption of MG dye, Cu +2 and Ni +2 . The remarkable adsorption capacities with higher reusability characteristics for adsorption of organic pollutants as well as inorganic heavy metals entrusts this activated biochar as a potential cost-effective adsorbent to mitigate water pollution issue.