Memory decline correlates with increased plasma cytokines in amyloid-beta (1–42) rat model of Alzheimer’s disease

Dysregulation of inflammatory markers like cytokines is implicated in the pathophysiology of Alzheimer’s disease (AD). Altered level of these cytokines show that pathogenesis of AD is beyond dysfunction of neurons resulting from amyloid beta accumulation but involves neuroinflammatory mechanisms elicited by the neuroimmune cell. In this study, we investigated the effect of amyloid-beta (1–42) (Aβ(1–42)) on memory and how inflammatory markers...