Review paper
Modulators of calpain activity: inhibitors and activators as potential drugs
Abstract
Introduction: Calpains are intracellular Ca2+-dependent cysteine proteases with 15 known members in the enzyme family. They act as regulatory enzymes, their cleavage modifying the function of their substrates. As their substrates have important roles in many physiological processes, adequate function of calpains is mandatory for normal cellular functions. The adverse operation of them is often related to diseases (e.g. neurodegenerative...
Paper Details
Title
Modulators of calpain activity: inhibitors and activators as potential drugs
Published Date
Feb 5, 2020
Volume
15
Issue
4
Pages
471 - 486
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