Differential Impact of Weight Loss and Glycemic Control on Inflammasome Signaling

Objective Interleukin (IL)‐1β is involved in obesity‐associated inflammation and in the pathogenesis of type 2 diabetes (T2D) mellitus. Our aim was to correlate serum IL‐1β and caspase‐1 levels with weight loss, glucose metabolism, and insulin resistance (IR) after bariatric surgery. Methods A total of 32 patients with morbid obesity and T2D (Ob‐T2D) and 29 patients with morbid obesity and normal glucose tolerance (Ob‐NGT), treated by Roux‐en‐Y...