Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity
Abstract
Infectious colitis is one of the most common health issues worldwide. Microfold (M) cells actively transport luminal antigens to gut-associated lymphoid tissue to induce IgA responses; however, it remains unknown whether M cells contribute to the induction of cellular immune responses. Here we report that M cell-dependent antigen transport plays a critical role in the induction of Th1, Th17, and Th22 responses against gut commensals in the...
Paper Details
Title
Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity
Published Date
Jul 1, 2020
Journal
Volume
13
Issue
4
Pages
679 - 690
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