Internal medicine

Public health

Pathology

Disease

Coronavirus disease 2019 (COVID-19)

Family medicine

Infectious disease (medical specialty)

Outbreak

Surgery

Political science

Intensive care medicine

China

Virology

Presentation (obstetrics)

Coronavirus

Pneumonia

2019-20 coronavirus outbreak

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Medicine

Environmental health

New England Journal of Medicine

An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.

First Case of 2019 Novel Coronavirus in the United States