Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes
Abstract
Zika virus (ZIKV) infection in the human central nervous system (CNS) causes Guillain–Barre syndrome, cerebellum deformity, and other diseases. Astrocytes are immune response cells in the CNS and an important component of the blood–brain barrier. Consequently, any damage to astrocytes facilitates the spread of ZIKV in the CNS. Connective tissue growth factor/Nephroblastoma overexpressed gene family 1 (CCN1), an important inflammatory factor...
Paper Details
Title
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes
Published Date
Jan 20, 2020
Journal
Volume
11
Issue
1
Pages
113 - 131
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