mTOR at the nexus of nutrition, growth, ageing and disease

Volume: 21, Issue: 4, Pages: 183 - 203
Published: Jan 14, 2020
Abstract
The mTOR pathway integrates a diverse set of environmental cues, such as growth factor signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half decades, mapping of the mTOR signalling landscape has revealed that mTOR controls biomass accumulation and metabolism by modulating key cellular processes, including protein synthesis and autophagy. Given the pathway's central role in maintaining cellular and...
Paper Details
Title
mTOR at the nexus of nutrition, growth, ageing and disease
Published Date
Jan 14, 2020
Volume
21
Issue
4
Pages
183 - 203
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