Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia

Volume: 40, Issue: 12, Pages: 2505 - 2520
Published: Jan 7, 2020
Abstract
Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria and a potent inflammatory stimulus for the innate immune response via toll-like receptor (TLR) 4 activation. Type 2 diabetes is associated with changes in gut microbiota and impaired intestinal barrier functions, leading to translocation of microbiota-derived LPS into the circulatory system, a condition referred to as metabolic endotoxemia. We...
Paper Details
Title
Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia
Published Date
Jan 7, 2020
Volume
40
Issue
12
Pages
2505 - 2520
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.