Internal medicine

Microbiome

Inflammatory bowel disease

Disease

Antibiotics

Gut flora

Bioinformatics

Biology

Microbiology

Immunology

Crohn's disease

Ulcerative colitis

Medicine

Immune system

Human microbiome

Journal of Allergy and Clinical Immunology

Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is thought to develop as a result of interactions between environmental, microbial, and immune-mediated factors in a genetically susceptible host. Of late, the potential role of the microbiome in the development, progression, and treatment of IBD has been a subject of considerable interest and enquiry. Indeed, studies in human subjects have shown that the gut microbiome is different in patients with IBD compared with that in healthy control subjects.

The microbiome and inflammatory bowel disease