Micro, Small and Medium Enterprises (MSMEs) are often referred to one of the pillars of the economic strength of a region. MSMEs have a very strategic and important role in national economic development. MSMEs have a role in distributing the results of development and also play a role in economic growth and employment. Now innovation in business transactions using new technology will greatly affect business activities, especially for MSMEs. One of the innovations currently developing is Electronic Money (e-money). The development of e-money technology facilitates retail transactions for both consumers and traders. In terms of MSME actors themselves, their readiness to use e-money technology is not yet known. This study aims to determine the level of readiness of MSMEs in using e-money. The model used to analyze the readiness of MSMEs in using e-money uses the Unified Theory of Acceptance and Use of Technology (UTAUT) model. Of the five hypotheses proposed, all hypotheses were declared accepted. Based on this research, it can be seen that the concept of e-money can be applied to MSMEs in Yogyakarta.