Biomimetic Platinum Nanozyme Immobilized on 2D Metal–Organic Frameworks for Mitochondrion-Targeting and Oxygen Self-Supply Photodynamic Therapy

Photodynamic therapy (PDT) as a noninvasive therapy mode has attracted considerable attention in the field of oncotherapy. However, the PDT efficacy is restricted either by the tumor hypoxia environment or the inherent properties of photosensitizers (PSs) including bad water solution, photobleaching, and easy aggregation. Herein, we designed and synthesized a new two-dimensional (2D) metal–organic framework, Sm-tetrakis(4-carboxyphenyl)porphyrin...