Iloprost inhibits acute allergic nasal inflammation by GATA3 -ILC2 pathway in mice

Acute allergic nasal inflammation is very common in the clinical allergic diseases, Prostaglandin I2 (PGI2) has been found to effective in combating inflammation. Iloprost, as an analog of PGI2, whose role and mechanisms in the acute allergic nasal inflammation remains unclear. It’s necessary to elucidate the efficacy and potential mechanism of Iloprost in acute allergic nasal inflammation. 36 female mice were randomly divided into DMSO group,...