ERK1 indicates good prognosis and inhibits breast cancer progression by suppressing YAP1 signaling
Abstract
The mitogen-activated protein kinase/extracellular signal-regulated (MAPK/ERK) pathway is a well-characterized signaling pathway during the development of various cancer types. ERK1 and ERK2, the two kinase effectors of MAPK cascade, exhibit high similarity. However, it is still unknown whether these two kinases are functionally different or in contrast functionally redundant during the development of breast cancer. We found that ERK1 expression...
Paper Details
Title
ERK1 indicates good prognosis and inhibits breast cancer progression by suppressing YAP1 signaling
Published Date
Dec 18, 2019
Journal
Volume
11
Issue
24
Pages
12295 - 12314
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