doi.org/10.1038/s41598-019-55723-5
Original paper

Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease

..., Sang Gu Kang
16
Scientific Reports3.80
Volume: 9, Issue: 1
Published: Dec 13, 2019
Abstract
Dengue virus (DENV) infection causes serious health problems in humans for which no drug is currently available. Recently, DENV NS2B-NS3 protease has been proposed as a primary target for anti-dengue drug discovery due to its important role in new virus particle formation by conducting DENV polyprotein cleavage. Triterpenoids from the medicinal fungus Ganoderma lucidum have been suggested as pharmacologically bioactive compounds and tested as...
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Paper Details
Title
Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease
DOI
doi.org/10.1038/s41598-019-55723-5
Published Date
Dec 13, 2019
Journal
Scientific Reports
Volume
9
Issue
1
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