Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation

Volume: 16, Issue: 1
Published: Dec 1, 2019
Abstract
Neuroinflammation constitutes a pathogenic process leading to neurodegeneration in several disorders, including Alzheimer's disease, Parkinson's disease (PD) and sepsis. Despite microglial cells being the central players in neuroinflammation, astrocytes play a key regulatory role in this process. Our previous results indicated that pharmacologic-antagonism or genetic deficiency of dopamine receptor D3 (DRD3) attenuated neuroinflammation and...
Paper Details
Title
Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation
Published Date
Dec 1, 2019
Volume
16
Issue
1
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