3D printing of a poly(vinyl alcohol)-based nano-composite hydrogel as an artificial cartilage replacement and the improvement mechanism of printing accuracy

Published on Jan 29, 2020in Journal of Materials Chemistry B5.344
· DOI :10.1039/C9TB02278C
Yeqiao Meng1
Estimated H-index: 1
(Sichuan University),
Jinlong Cao4
Estimated H-index: 4
(Sichuan University)
+ 2 AuthorsLin Ye19
Estimated H-index: 19
(Sichuan University)
Sources
Abstract
Inspired by the gradient structure of articular cartilage, poly(vinyl alcohol) (PVA)-based composite hydrogel with biomimetic gradient structure as artificial cartilage replacement was constructed by extrusion 3D printing technique. The influence of concentration and composition of the PVA-based solution on its rheological behavior and printability was studied, and the improving mechanism for 3D printing accuracy of the hydrogel was explored: introduction of GO or GO-HA gave rise to the weakened inter-molecular hydrogen bonds and entanglement density simultaneously, and the dynamic viscosity was highly improved. Therefore, the solution exhibited enhanced shear-thinning behavior in the range of printing shear rate and reduced Barus effect, thus highly improving the printability and printing accuracy of the samples. The 3D printing of PVA hydrogels was successfully achieved, and the printing biomimetic gradient samples possessed qualified compressive and tribological properties, which showed promising potentials in developing precisely customized repairment for artificial cartilage.
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