Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering

Volume: 573, Pages: 118827 - 118827
Published: Jan 1, 2020
Abstract
Uniform drug distribution within fast disintegrating tablets is a key quality measure to ensure a reliable, steady, and targeted release of the contained active pharmaceutical ingredients. In this work, the drug particle distribution in mini-tablets was studied with synchrotron phase contrast X-ray microtomography. Mini-tablets had a weight of 9.5 mg and a drug load from 2.5% to 20%. Moxidectin, a drug used for treatment of parasitic infections,...
Paper Details
Title
Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering
Published Date
Jan 1, 2020
Volume
573
Pages
118827 - 118827
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