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Original paper

MBD-seq - realities of a misunderstood method for high-quality methylome-wide association studies

Volume: 15, Issue: 4, Pages: 431 - 438
Published: Nov 19, 2019
Abstract
The majority of methylome-wide association studies (MWAS) have been performed using commercially available array-based technologies such as the Infinium Human Methylation 450K and the Infinium MethylationEPIC arrays (Illumina). While these arrays offer a convenient and relatively robust assessment of the probed sites they only allow interrogation of 2-4% of all CpG sites in the human genome. Methyl-binding domain sequencing (MBD-seq) is an...
Paper Details
Title
MBD-seq - realities of a misunderstood method for high-quality methylome-wide association studies
Published Date
Nov 19, 2019
Volume
15
Issue
4
Pages
431 - 438
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