#1Mu-Ke Tao(CAS: Chinese Academy of Sciences)H-Index: 3
#2Min Xu(CAS: Chinese Academy of Sciences)H-Index: 22
Last. Ying-Jun Zhang(CAS: Chinese Academy of Sciences)H-Index: 28
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A new methylene-bridged dimeric flavonol glycoside, methylenebisnicotiflorin (1), was isolated from ripe Pu-er tea, along with 10 known flavonoids (2-11) and seven known phenolic compounds (12-18). The structure elucidation was based on spectroscopic analysis. Among them, 1,3-dihydroxyphenyl-2-O-sulfate (13), 2,3,4-trihydroxybenzoic acid (16) and 3,3,4,4-tetrahydroxybiphenyl (18) are reported from tea plants for the first time.
#6L. P. Zhang(AAU: Anhui Agricultural University)H-Index: 1
AbstractFuzhuan brick-tea (FBT) is unique for a fungal fermentation stage in its manufacture process and is classified in dark tea. A new acylated flavonol glycoside, kaempferol 3-O-[E-p-coumaroyl-(→2)][α-l-arabinopyranosyl-(1→3)][α-l-rhamnopyranosyl(1→6)]-β-d-glucopyranoside, which was trivially named as camellikaempferoside A (1), was isolated from FBT along with camelliquercetiside C (2). Their structures were unambiguously elucidated by combination of spectroscopic and chemical methods. Comp...
The isolation and evaluation of inhibitors of Fanconi F protein (FANCF) – hairy and enhancer of split 1 (Hes1) complex are described. A high-throughput screening assay for small-molecule inhibitors of the FANCF–Hes1 complex was realized. Successful complex formation between fluorophore (Cy3)-labeled human FANCF and immobilized rat or human HES1 on a microplate was established. Screening of our plant extract library using this system resulted in the isolation of eight natural products, including ...
#1Hong Hanh Thi Tran(VAST: Vietnam Academy of Science and Technology)H-Index: 1
#2Minh Chau Nguyen(HUST: Hanoi University of Science and Technology)H-Index: 1
Last. Tien Dat Nguyen(VAST: Vietnam Academy of Science and Technology)H-Index: 9
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AbstractContext: A methanol extract of Cyperus rotundus L. (Cyperaceae) rhizomes showed inhibitory activity against α-glucosidase and α-amylase, two enzymes involve in carbohydrate digestion.Objective: Identification of compounds from C. rotundus rhizomes responsible for the inhibition of α-glucosidase and α-amylase.Materials and methods: Compounds were identified by a phytochemical investigation using combined chromatographic and spectroscopic methods. α-glucosidase and α-amylase inhibitory act...
Theacrine (1,3,7,9-tetramethyluric acid), a purine alkaloid, has proven to be beneficial in maintaining several brain functions and is being studied for potential medicinal uses in recent years. In this study, we isolated theacrine from Camellia assamica var. kucha and investigated its protective effects on liver damage induced by restraint stress in mice. Results showed that 18 h of restraint stress could induce liver damage, with an obvious increase in levels of plasma alanine aminotransferase...
Last. Surk-Sik Moon(KNU: Kongju National University)H-Index: 25
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Abstract Four new quercetin acylglycosides, designated camelliquercetisides A–D, quercetin 3- O -[α- l -arabinopyranosyl(1→3)][2- O ″ - ( E )- p -coumaroyl][β- d -glucopyranosyl(1→3)-α- l -rhamnopyranosyl(1→6)]-β- d -glucoside ( 17 ), quercetin 3- O -[2- O ″-( E )- p -coumaroyl][β- d -glucopyranosyl(1→3)-α- l -rhamnopyranosyl(1→6)]-β- d -glucoside ( 18 ), quercetin 3- O -[α- l -arabinopyranosyl(1→3)][2- O ″-( E )- p -coumaroyl][α- l -rhamnopyranosyl(1→6)]-β- d -glucoside ( 19 ), and quercetin 3-...
Abstract White tea (WT) is very similar to green tea (GT) but it is exceptionally prepared only from the buds and young tea leaves of Camelia sinensis plant while GT is prepared from the matured tea leaves. The present study was investigated to examine the effects of a 0.5% aqueous extract of WT in a streptozotocin-induced diabetes model of rats. Six-week-old male Sprague-Dawley rats were divided into 3 groups of 6 animals in each group namely: normal control (NC), diabetic control (DBC) and dia...
Abstract The foliar metabolome of Cladrastis kentukea (Leguminosae) contains a complex mixture of flavonoids including acylated derivatives of the 3- O -rhamnosyl(1 → 2)[rhamnosyl(1 → 6)]-galactosides of kaempferol and quercetin and their 7- O -rhamnosides, together with an array of non-acylated kaempferol and quercetin di-, tri- and tetraglycosides. Thirteen of the acylated flavonoids, 12 of which had not been reported previously, were characterised by spectroscopic and chemical methods. Eight ...
#2Bui Huu Tai(CNU: Chungnam National University)H-Index: 22
Last. Young Ho Kim(CNU: Chungnam National University)H-Index: 94
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Abstract One new ursane-type triterpenoid glycoside, asiaticoside G ( 1 ), five triterpenoids, asiaticoside ( 2 ), asiaticoside F ( 3 ), asiatic acid ( 4 ), quadranoside IV ( 5 ), and 2α,3β,6β-trihydroxyolean-12-en-28-oic acid 28- O -[α- l -rhamnopyranosyl-(1→4)-β- d -glucopyranosyl-(1→6)-β- d -glucopyranosyl] ester ( 6 ), and four flavonoids, kaempferol ( 7 ), quercetin ( 8 ), astragalin ( 9 ), and isoquercetin ( 10 ) were isolated from the leaves of Centella asiatica. Their chemical structures...
#1Yuanfeng Wang(SHNU: Shanghai Normal University)H-Index: 21
#2Zhiwei Yang(SHNU: Shanghai Normal University)H-Index: 4
Last. Xinlin Wei(SHNU: Shanghai Normal University)H-Index: 20
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The sugar compositions, α-glucosidase inhibitory and α-amylase inhibitory activities of polysaccharides from leaves and flowers of green tea (Camellia sinensis) obtained by hot water extraction (HWE), boiled water extraction (BWE) and enzymatic extraction (EE) were investigated. The yields, sugar contents and monosaccharide compositions of tea leaves polysaccharides (TLPS) and tea flower polysaccharides (TFPS) were all significantly affected by extraction methods. The contents of acidic polysacc...
Abstract Four new dihydrostilbene glycosides, assastilbosides A–D (1-4), along with seven known compounds, 5,4′-dihydroxydihydrostilbene 3-O-β- d -glucopyranoside (5), 3,5-dihydroxydihydrostilbene 4′-O-β- d -glucopyranoside (6), 3,5-dihydroxydihydrostilbene 4′-O-[6′′-O-(4′′′-methoxy)galloyl]-β- d -glucopyranoside (7), 3,5-dimethoxydihydrostilbene 4′-O-α- l -rhamnopyranosyl-(1→6)-β- d -glucopyranoside (8), ()-epicatechin (9), ()-epicatechin 3-O-gallate (10), and (-)-epigallocatechin 3-O-gallate...
Abstract Three new bis-trinorcadalenes, bistrinorcadintermes A–C (1-3) along with seven known compounds, parvifloral D (4), parvifloral E (5), parvifloral C (6), hymexelsin (7), scopoletin (8), scopolin (9), and hibiscolactone A (10) were isolated from the aerial parts and radix of Decaschistia intermedia Craib. Their chemical structures were determined based on spectroscopic methods, including 1D, 2D NMR, MS, and experimental CD spectra. All compounds were evaluated for their α-glucosidase inhi...
Abstract Two new cadinane sesquiterpenes, cadinoschanes A and B (1 and 2), one new norlignan, lignanoschane A (6) along with seven known compounds, hibiscone B (3), 7β-O-β-glucopyranosyl bombaxone (4), 2,7β,8β-trihydroxy trans-calamenene 7-O-β-D-glucopyranoside (5), clemastanin A (7), (−)-3,4,3′,4′-tetrahydroxy-9,7′β-epoxylignano-7β,9′-lactone (8), N-trans-feruloyl tyramine (9), and methyl (3R)-3-[(3R)-3-{(3R)-3-hydroxybutanoyloxy} butanoyloxy} butanoate (10) were isolated from Abelmoschus mosch...
