Identification (biology)

Internal medicine

Genetic testing

Colorectal cancer

Bioinformatics

Genetic counseling

Biology

Cancer

Risk assessment

Oncology

Intensive care medicine

Lynch syndrome

Computer science

Botany

Computer security

Genetics

DNA mismatch repair

Medicine

Journal of the National Comprehensive Cancer Network

Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019