Infertility

Biology

Andrology

Male infertility

Sperm motility

Semen

Asthenozoospermia

Semen analysis

Pregnancy

Sperm

Cell biology

Genetics

Motility

Medicine

Andrologia

Semen sample with poor sperm motility, which called asthenozoospermia, is considered as one of the main factors contributing to male infertility. Recognition of the cellular and molecular pathways contributing to sperm motility reduction may lead to applying novel treatment strategies for overcoming low sperm motility in asthenozoospermia individuals. In this review, we intend to discuss the main causes of sperm motility reduction in asthenozoospermia and some treatment strategies used to overcome low sperm motility.

Asthenozoospermia: Cellular and molecular contributing factors and treatment strategies