MiR-29a promotes osteogenic differentiation of mesenchymal stem cells via targeting HDAC4.

Objective null To investigate the role of miR-29a in regulating the differentiation mesenchymal stem cells into osteoblasts. null Materials and methods null For the first step, the changes of expression of miR-29a during the process of mesenchymal stem cells (MSCs) differentiation into osteoblast were detected. Then, we infected the MSCs with mimics or inhibitors of miR-29a to explore the roles of miR-29a in the differentiation. Further, the...