Single Cell Analysis of Endothelial Cells Identified Organ-Specific Molecular Signatures and Heart-Specific Cell Populations and Molecular Features

The endothelial cell exists in the whole body by lining the inner surface of vasculature and plays an important role in normal physiology and disease progressions. Each organ should have a heterogeneous population of endothelial cells, but these heterogeneities have not been systematically analyzed at single cell level. The Tabular Muris project profiled mouse single cells from 20 organs, which includes endothelial cells in 10 organs....