Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
Abstract
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the development of itch and the acute-to-chronic itch transition remain unknown. Here, we show that skin-infiltrating neutrophils are key initiators of itch in atopic dermatitis, the most prevalent chronic...
Paper Details
Title
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
Published Date
Oct 21, 2019
Journal
Volume
8
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History