Alternative scaffolds in radionuclide diagnosis of malignancies
Abstract
This review discusses a relatively new class of targeted molecules that is being actively studied for radionuclide diagnosis and treatment of malignancies. The full-size antibodies used so far have non-optimal pharmacological properties, slow distribution in the body, poor penetration into the tissue and kidney excretion, and high immunogenicity, which significantly complicates their use in clinical practice. Over the past decade, a new class of...
Paper Details
Title
Alternative scaffolds in radionuclide diagnosis of malignancies
Published Date
Oct 27, 2019
Journal
Volume
18
Issue
3
Pages
125 - 133
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History