Internal medicine

Disease

Tick

Veterinary medicine

Immunoglobulin E

Intensive care medicine

Antibody

Immunology

Allergy

Allergic reaction

Medicine

The Journal of Allergy and Clinical Immunology In Practice

The galactose-α-1,3-galactose (α-Gal) syndrome has many novel features that are relevant to diagnosis and management. In most cases, the diagnosis can be made on a history of delayed allergic reactions to mammalian meat and the blood test for IgE to the oligosaccharide α-Gal. In general, the diagnosis also dictates the primary treatment, that is, avoiding mammalian meat and also dairy in some cases. In the United States, the lone star tick is the primary cause of this disease, but different ticks are responsible in other countries.

Diagnosis and Management of Patients with the α-Gal Syndrome