Internal medicine

Particle therapy

Medical physics

Environmental science

Radiation therapy

Medicine

Physica Medica

Particle Therapy (PT) is a tumor control technique that makes use of charged ion beams targeting the tumor region inside a patient to maximize the biological damage to the cancer cells while sparing the surrounding healthy tissues [1]. These characteristics are directly related to the energy loss mechanism of charged ions inside matter, which results in the Bragg Peak (BP) shape of the associated dose release. The spatial selectivity as well as the biological damage inflicted to the cells are furthermore enhanced when ions with Z>1 are used, due to their higher Relative Biological Effectiveness (RBE) and the reduced Oxygen Enhancement Ratio (OER)[2,3].

Review and performance of the Dose Profiler, a particle therapy treatments online monitor