Original paper
Expression, purification, and cytotoxic evaluation of IL24-BR2 fusion protein
Abstract
Interleukin (IL) 24 is a pro-inflammatory and tumor suppressor cytokine capable of inducing selective apoptosis in various cancer cells. BR2, on the other hand, is an anti-microbial peptide with selective penetrability to the cancer cells. In this study, we aimed to produce and purify a fusion protein containing IL24 as the toxic moiety fused to BR2, as targeting moiety, and then to evaluate its cytotoxic activities. For this purpose, the coding...
Paper Details
Title
Expression, purification, and cytotoxic evaluation of IL24-BR2 fusion protein
Published Date
Jan 1, 2019
Volume
14
Issue
4
Pages
320 - 320
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Notes
History